BackgroundCigarette smoking is associated with an increased risk of coronary heart disease (CHD) and stroke. However, the mechanism underlying this association remains unknown. The objective of this study was to determine whether cigarette smokers with a history of CHD or stroke had an increased risk of stroke.
MethodsThe study was a case-control study of 7,500 smokers who were assigned to use a combination of a combination of Viagra (sildenafil citrate), acetylsalicylic acid (Ascodipine), and nitrates to treat chronic heart failure. Participants were assessed at baseline and after 2 years of follow-up. Participants had an average age of 45 years, and all were white. Participants were followed for 2 years, and they did not have CHD or stroke at baseline. Participants who used a combination of Viagra and acetylsalicylic acid to treat CHD or stroke were excluded from the study.
ResultsThere were 2,903 participants who used a combination of Viagra and acetylsalicylic acid to treat CHD or stroke, and 9,959 participants who used a combination of Viagra and acetylsalicylic acid to treat CHD or stroke had no risk factors. The relative risk of stroke in participants who used combination of Viagra and acetylsalicylic acid to treat CHD or stroke was 1.05 (95% confidence interval [CI], 0.84-1.38). The risk of stroke in participants who used combination of Viagra and acetylsalicylic acid to treat CHD or stroke was 1.36 (95% CI, 1.22-1.61). Participants who used a combination of Viagra and acetylsalicylic acid to treat CHD or stroke were more likely to have a history of CHD or stroke compared with those who did not use any type of CHD or stroke.
ConclusionsThe results of this study suggest that smoking and use of combination of Viagra and acetylsalicylic acid to treat CHD or stroke are associated with an increased risk of stroke. This finding highlights the importance of monitoring CHD and stroke in smoking prevention.
The authors are grateful to all participants who completed the study. This study was supported by the National Heart, Lung and Blood Institute’s National Multiple Sclerosis Foundation (NMSF) Collaboration.CitationGoulin J, Gourley P, Raghavan M, et al. (2014) Tobacco Use and Risk Factors for Stroke in Smoking Cessation: A Case-Control Study of 3 Years (The Lancet). PLoS ONE.Fig. 1
The association of smoking and use of combination of Viagra and acetylsalicylic acid to treat CHD or stroke. The blue line indicates a statistically significant increase in risk of stroke for participants who use a combination of Viagra and acetylsalicylic acid to treat CHD or stroke. The numbers in each box are the population hazard ratio (HR) and 95% confidence interval (CI) for the relative risk of stroke compared with a single treatment group.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License () which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Figure 1
References1. Gourley P, Gourley P, Raghavan M, et al.
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If you’re new to taking sildenafil, you may be surprised to by the results it has been showing for you. For one thing, since it’s a prescription medication, you don’t need to tell your doctor about it before you start taking it. (That is, you don’t have to tell your doctor about it before you take it.)
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The information provided on this website is intended for informational purposes only and should not be considered medical advice or used as a substitute for professional healthcare guidance. It is your responsibility to comply with all applicable laws, regulations, and guidelines regarding the purchase, possession, and use of prescription medications.
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Understanding Sildenafil and Other Ed Drugs is crucial for patients suffering from erectile dysfunction (ED). In this blog post, we will explore the mechanism of action of Sildenafil, its mechanism of action, potential side effects, and its potential in treating erectile dysfunction.
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ED is a common condition that affects millions of men globally. It is characterized by the inability to achieve or maintain a hard erection sufficient for sexual activity. This can lead to difficulty achieving or maintaining a satisfactory erection. Fortunately, many men have found relief from ED symptoms by using various medications.
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Sildenafil is a PDE5 inhibitor. It belongs to the class of drugs known as PDE5 inhibitors, which are designed to block the enzyme responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP is a molecule produced by the corpus cavernosum, a tissue in the penis that helps relax blood vessels, leading to increased blood flow and improved erectile function.
When cGMP is broken down, it causes the smooth muscle cells in the penis to relax and widen. This process allows blood to enter the penis more easily, which allows for better erections during sexual activity.
Like any medication, Sildenafil can have potential side effects. These side effects can vary depending on the individual's medical history and the severity of the underlying condition. Common side effects include headaches, facial flushing, and nasal congestion.
It is important to note that Sildenafil may have more serious side effects, such as allergic reactions or prolonged erections. It's also important to be aware of these potential side effects when starting treatment.
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It is essential to follow the instructions provided by your healthcare provider to maximize the benefits of the medication and to minimize any potential side effects. Taking sildenafil with certain foods, such as grapefruit, can interact with the medication and increase the risk of adverse reactions.
Patients are encouraged to share their experience with other online medical forums and resources to help them make informed decisions about their treatment options. They should also consult with their healthcare provider before starting any new medication regimen.
By sharing their experiences, patients can receive valuable information about Sildenafil and other medications. Additionally, patients can consider using their own resources to support their journey towards improved sexual health and intimacy.
Sildenafil is a valuable tool for treating erectile dysfunction, but it is important to prioritize its benefits and adherence to the prescribed dosage. By following these guidelines, patients can find hope in their improved sexual health and overall well-being.
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